In children with certain autism mutations, the diversity and severity of symptoms are often related to the identity and properties of gene units, called exons, targeted by the mutations.
The most detailed analysis to date of CRISPR genome editing in human embryos finds a significant risk of chromosomal abnormalities when using the technique at the earliest stage of human development.
Columbia researchers have uncovered an array of new genes that cause stillbirth, significantly increasing the understanding of the genetic foundations of a common, but little studied, condition.
Genetic changes that were believed meaningless may play an important yet overlooked role in human diseases, including breast cancer, a new study from Columbia University Irving Medical Center finds.
CUMC researchers have found direct evidence of a link between prenatal vitamin A deficiency and postnatal airway hyperresponsiveness, a hallmark of asthma.
High-risk pregnant women being recruited for a clinical trial that aims to give parents detailed information about genetic abnormalities found in utero.
Two Columbia faculty are part of a 61-member international research team that discovered 25 epilepsy-causing mutations in new and previously identified genes.