In the same way that ChatGPT understands human language, a new AI model developed by Columbia computational biologists captures the language of cells to accurately predict their activities.
A new study shows that some of our cells favor genes of one parent or the other and can explain a longstanding mystery of why some people with disease-causing genes experience no symptoms.
A new study finds that many of our genes, if disabled by a mutation, have a surprising ability to turn on backup genes to compensate for lost functions.
A “loopy” discovery in bacteria is raising fundamental questions about the makeup of our own genome. And revealing a potential wellspring of material for new genetic therapies.
In children with certain autism mutations, the diversity and severity of symptoms are often related to the identity and properties of gene units, called exons, targeted by the mutations.
The most detailed analysis to date of CRISPR genome editing in human embryos finds a significant risk of chromosomal abnormalities when using the technique at the earliest stage of human development.
Columbia researchers have uncovered an array of new genes that cause stillbirth, significantly increasing the understanding of the genetic foundations of a common, but little studied, condition.
Genetic changes that were believed meaningless may play an important yet overlooked role in human diseases, including breast cancer, a new study from Columbia University Irving Medical Center finds.
Based on the book by Columbia oncologist Siddhartha Mukherjee, the documentary also features Wendy Chung, David Goldstein, Samuel Sternberg, and Nancy Wexler. The two-part series airs April 7 and 14.
By participating in one of the world’s largest genetic studies, New Yorkers will help bring precision medicine to their communities, Columbia’s David Goldstein explains.
Columbia's Sandra Soo-Jin Lee leads a national study on the inclusion of ethnic minorities in genetic studies with a goal of enhancing precision medicine.
A new study shows how certain cells ‘cheat’ during cell competition to eliminate their neighbors and take over tissues; the findings could point toward new strategies for treating cancer.
Lorraine S. Symington, PhD, the Harold S. Ginsberg Professor of Microbiology & Immunology, has been elected to the American Academy of Arts and Sciences.