A “loopy” discovery in bacteria is raising fundamental questions about the makeup of our own genome. And revealing a potential wellspring of material for new genetic therapies.
Researchers at Columbia University College of Dental Medicine have engineered exosomes to carry CRISPR, significantly enhancing the delivery of genome editing components to specific cells and tissues.
Including BRCA1 testing with prenatal carrier screening could identify people at risk of breast, ovarian, and pancreatic cancer at a time when cancer screening could save their lives.
Columbia genome engineers are designing a CRISPR-based gene therapy with potential to prevent blindness in anyone with retinitis pigmentosa, a condition caused by more than 80 different genes.
Genetic changes that were believed meaningless may play an important yet overlooked role in human diseases, including breast cancer, a new study from Columbia University Irving Medical Center finds.
Based on the book by Columbia oncologist Siddhartha Mukherjee, the documentary also features Wendy Chung, David Goldstein, Samuel Sternberg, and Nancy Wexler. The two-part series airs April 7 and 14.
By participating in one of the world’s largest genetic studies, New Yorkers will help bring precision medicine to their communities, Columbia’s David Goldstein explains.
Columbia's Sandra Soo-Jin Lee leads a national study on the inclusion of ethnic minorities in genetic studies with a goal of enhancing precision medicine.
A new study shows how certain cells ‘cheat’ during cell competition to eliminate their neighbors and take over tissues; the findings could point toward new strategies for treating cancer.
Lorraine S. Symington, PhD, the Harold S. Ginsberg Professor of Microbiology & Immunology, has been elected to the American Academy of Arts and Sciences.
Jeffrey Hall, Michael Rosbash, and Michael Young were awarded the 2017 Nobel Prize in Physiology or Medicine for their discoveries of molecular mechanisms controlling circadian rhythm.