In children with certain autism mutations, the diversity and severity of symptoms are often related to the identity and properties of gene units, called exons, targeted by the mutations.
The most detailed analysis to date of CRISPR genome editing in human embryos finds a significant risk of chromosomal abnormalities when using the technique at the earliest stage of human development.
Columbia researchers have uncovered an array of new genes that cause stillbirth, significantly increasing the understanding of the genetic foundations of a common, but little studied, condition.
Genetic changes that were believed meaningless may play an important yet overlooked role in human diseases, including breast cancer, a new study from Columbia University Irving Medical Center finds.
Studies answer an old debate in developmental biology: How do cells destined to form a particular tissue or structure remember what they're supposed to be?
Solving a 60-year-old medical mystery, a team led by Columbia researchers has discovered what causes kidney and urinary tract defects in people with DiGeorge syndrome.
For some types of autism, gastrointestinal problems may originate from the same genetic changes that lead to the behavioral and social characteristics of the condition.
College of Physicians & Surgeons Dean Lee Goldman discusses his new book, which examines the role DNA plays in attempting to treat diabetes, obesity, and cardiovascular disease.