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In children with certain autism mutations, the diversity and severity of symptoms are often related to the identity and properties of gene units, called exons, targeted by the mutations.
The most detailed analysis to date of CRISPR genome editing in human embryos finds a significant risk of chromosomal abnormalities when using the technique at the earliest stage of human development.
Columbia researchers have uncovered an array of new genes that cause stillbirth, significantly increasing the understanding of the genetic foundations of a common, but little studied, condition.
- March 27, 2017
Studies answer an old debate in developmental biology: How do cells destined to form a particular tissue or structure remember what they're supposed to be?
- January 25, 2017
Solving a 60-year-old medical mystery, a team led by Columbia researchers has discovered what causes kidney and urinary tract defects in people with DiGeorge syndrome.
- August 16, 2016
Expanded prenatal genetic testing may increase the detection of carriers for a variety of potentially serious conditions.
- June 1, 2016
Columbia oncologist and Pulitzer Prize-winning author Siddhartha Mukherjee talks about why he wrote his latest book, "The Gene: An Intimate History."
- April 25, 2016
For some types of autism, gastrointestinal problems may originate from the same genetic changes that lead to the behavioral and social characteristics of the condition.
- January 26, 2016
College of Physicians & Surgeons Dean Lee Goldman discusses his new book, which examines the role DNA plays in attempting to treat diabetes, obesity, and cardiovascular disease.
- January 12, 2016
Wayne Frankel, the newest member of the Institute for Genomic Medicine, says recent advances in gene discovery and editing are illuminating epilepsy.