Columbia genome engineers are designing a CRISPR-based gene therapy with potential to prevent blindness in anyone with retinitis pigmentosa, a condition caused by more than 80 different genes.
Many Black Americans thought to have a high risk of developing kidney disease possess a genetic variant that eradicates the extra risk, a new study from Columbia researchers has found.
The genetic changes that made it possible for humans to walk upright have been uncovered in a study that also shows how slight variations in skeletal proportions are linked to arthritis.
Scientists from around the world attended a symposium at Columbia to celebrate the 80th birthday of Tom Maniatis and his contributions to the field of molecular biology.
Columbia's Wendy Chung, the original plaintiff in the case against Myriad Genetics, says the Supreme Court decision banning gene patents will open a new era of genomic medicine.
A study of children born with severe heart defects has found that at least 10 percent of cases stem from genetic mutations that occur spontaneously early in development.
Columbia Magazine reports on an NIH-funded study, led by Dr. Ronald Wapner, where thousands of women were provided microarray, a powerful genetic test, for prenatal testing.
The largest genome-wide search for Alzheimer’s genes in African-Americans has found that African-Americans with a variant of the ABCA7 gene have almost double the risk of developing late-onset Alzheimer’s disease.