In children with certain autism mutations, the diversity and severity of symptoms are often related to the identity and properties of gene units, called exons, targeted by the mutations.
The most detailed analysis to date of CRISPR genome editing in human embryos finds a significant risk of chromosomal abnormalities when using the technique at the earliest stage of human development.
Columbia researchers have uncovered an array of new genes that cause stillbirth, significantly increasing the understanding of the genetic foundations of a common, but little studied, condition.
Genetic changes that were believed meaningless may play an important yet overlooked role in human diseases, including breast cancer, a new study from Columbia University Irving Medical Center finds.
The largest genome-wide search for Alzheimer’s genes in African-Americans has found that African-Americans with a variant of the ABCA7 gene have almost double the risk of developing late-onset Alzheimer’s disease.
A team of scientists from The New York Stem Cell Foundation Laboratory and CUMC has developed a technique that may prevent the inheritance of mitochondrial diseases in children.