In children with certain autism mutations, the diversity and severity of symptoms are often related to the identity and properties of gene units, called exons, targeted by the mutations.
The most detailed analysis to date of CRISPR genome editing in human embryos finds a significant risk of chromosomal abnormalities when using the technique at the earliest stage of human development.
Columbia researchers have uncovered an array of new genes that cause stillbirth, significantly increasing the understanding of the genetic foundations of a common, but little studied, condition.
Genetic changes that were believed meaningless may play an important yet overlooked role in human diseases, including breast cancer, a new study from Columbia University Irving Medical Center finds.
Columbia's Wendy Chung, the original plaintiff in the case against Myriad Genetics, says the Supreme Court decision banning gene patents will open a new era of genomic medicine.
A study of children born with severe heart defects has found that at least 10 percent of cases stem from genetic mutations that occur spontaneously early in development.
Columbia Magazine reports on an NIH-funded study, led by Dr. Ronald Wapner, where thousands of women were provided microarray, a powerful genetic test, for prenatal testing.