Columbia genome engineers are designing a CRISPR-based gene therapy with potential to prevent blindness in anyone with retinitis pigmentosa, a condition caused by more than 80 different genes.
Many Black Americans thought to have a high risk of developing kidney disease possess a genetic variant that eradicates the extra risk, a new study from Columbia researchers has found.
The genetic changes that made it possible for humans to walk upright have been uncovered in a study that also shows how slight variations in skeletal proportions are linked to arthritis.
Scientists from around the world attended a symposium at Columbia to celebrate the 80th birthday of Tom Maniatis and his contributions to the field of molecular biology.
For some types of autism, gastrointestinal problems may originate from the same genetic changes that lead to the behavioral and social characteristics of the condition.
College of Physicians & Surgeons Dean Lee Goldman discusses his new book, which examines the role DNA plays in attempting to treat diabetes, obesity, and cardiovascular disease.
P&S researcher Wendy Chung and colleagues find genetic mutations that explain why many children with congenital heart disease also have neurodevelopmental disorders.
Funding from the ALS Association and the Tow Foundation will be used by the New York Genome Center to determine the entire genetic sequence of people with ALS who donated their tissues after death.