A new study finds that many of our genes, if disabled by a mutation, have a surprising ability to turn on backup genes to compensate for lost functions.
A “loopy” discovery in bacteria is raising fundamental questions about the makeup of our own genome. And revealing a potential wellspring of material for new genetic therapies.
Researchers at Columbia University College of Dental Medicine have engineered exosomes to carry CRISPR, significantly enhancing the delivery of genome editing components to specific cells and tissues.
Including BRCA1 testing with prenatal carrier screening could identify people at risk of breast, ovarian, and pancreatic cancer at a time when cancer screening could save their lives.
Columbia University Medical Center (CUMC) is one of 50 institutions selected nationwide from more than 700 applications for a “Provocative Questions” grant from the National Cancer Institute (NCI).
A study by Columbia researchers Judith Miné-Hattab, PhD, and Rodney Rothstein, PhD, found that after a double-strand break in DNA, the mobility of both the broken segment and other, unbroken, chromosomes is greatly increased.