The genetic changes that made it possible for humans to walk upright have been uncovered in a study that also shows how slight variations in skeletal proportions are linked to arthritis.
Scientists from around the world attended a symposium at Columbia to celebrate the 80th birthday of Tom Maniatis and his contributions to the field of molecular biology.
In the GUARDIAN study, the genomes of newborns are being scanned to identify children who have one of hundreds of treatable and preventable rare genetic conditions before symptoms emerge.
A study by Columbia researchers Judith Miné-Hattab, PhD, and Rodney Rothstein, PhD, found that after a double-strand break in DNA, the mobility of both the broken segment and other, unbroken, chromosomes is greatly increased.
Richard S. Mann, PhD, and colleagues have solved the longstanding puzzle of why a single transcription factor can turn on many genes in a test tube, but only a few genes in a live organism.
Columbia University Medical Center (CUMC) researchers have found the first direct evidence that an acquired trait can be inherited without any DNA involvement.