Analysis of 1.6 million brain cells from older adults has captured the cellular changes that occur in Alzheimer’s early stages, revealing potential new targets and routes for prevention.
A new study finds that mitochondria in our brain cells frequently fling their DNA into the cells' nucleus, where the mitochondrial DNA integrates into chromosomes, possibly causing harm.
Columbia researchers found that exposure to famine early in gestation—but not in the first years of life or late gestation—increased the risk of developing type 2 diabetes decades later.
Researchers at the Mailman School of Public Health found that people who have lost someone close show signs of older biological age compared to those who haven't experienced such losses.
A 24-hour fast followed by feeding rejuvenates the blood-forming stem cells in old mice, a finding that may lead to new ways to help people live healthier lives as they age.
Warning letters from Medicare sent to high prescribers reduced prescriptions of risky antipsychotics for elderly people with dementia without negatively affecting patient health.
People with a history of cognitively stimulating occupations during their 30s, 40s, 50s, and 60s had a lower risk of mild cognitive impairment and dementia after age 70.
Columbia biomedical engineers are collaborating with orthopedic surgeons to build a living replacement knee to be tested in clinical trials within five years.
Columbia genome engineers are designing a CRISPR-based gene therapy with potential to prevent blindness in anyone with retinitis pigmentosa, a condition caused by more than 80 different genes.