Analysis of 1.6 million brain cells from older adults has captured the cellular changes that occur in Alzheimer’s early stages, revealing potential new targets and routes for prevention.
A new study finds that mitochondria in our brain cells frequently fling their DNA into the cells' nucleus, where the mitochondrial DNA integrates into chromosomes, possibly causing harm.
Columbia researchers found that exposure to famine early in gestation—but not in the first years of life or late gestation—increased the risk of developing type 2 diabetes decades later.
Researchers at the Mailman School of Public Health found that people who have lost someone close show signs of older biological age compared to those who haven't experienced such losses.
Using stem cells from patients, P&S researchers have created a model of age-related macular degeneration in a dish, which may lead personalized treatments to prevent vision loss.
A Columbia-led research team has clinically validated a new method for predicting time to nursing home residence or death for patients with Alzheimer’s.
Research to delay aging would have better population health and economic returns than advances in individual fatal diseases such as cancer or heart disease, according to Mailman study.