Events

Columbia Stem Cell Initiative (CSCI) Work in Progress (WIP) Series   Thursday, January 27 11:30 AM Zoom link: https://columbiacuimc.zoom.us/j/93214087784?pwd=WDJMSE92TGh6bHNPWkQrZktHQWtBZz09 Meeting ID: 932 1408 7784 Passcode: 329735   PRESENTERS: Kevin Sun/Bin Xu Lab Troy Anderson/Joanna Smeeton Lab   An opportunity for Columbia’s community at large to learn about ongoing stem cell works happening in the labs affiliated with CSCI, and for CSCI trainee to receive feedback from the community. Each event will include two presentations by trainees of 20-minutes each, with time afterward for Q&A.   For more info: ll3129@cumc.columbia.edu https://www.stemcell.columbia.edu/  

Alternative 3’UTR isoforms: do the ends justify the means? Bin Tian, PhD. The Wistar Institute Professor and Program Co-Leader, Gene Expression & Regulation Program, The Wistar Institute Cancer Center; Co-director, Center for Systems & Computational Biology  

José L. McFaline-Figueroa, PhD, Assistant Professor of Biomedical Engineering; Member, HICCC Precision Oncology and Systems Biology Program Probing the genetic basis of the response to exposure using single-cell genomics The response of cells to therapy depends on the nature of the exposure and the host's genetic background. Identifying the molecular signatures that define these interactions necessitates methods to probe the large combinatorial space between genes and exposures, ideally at a resolution that accounts for heterogeneity in response. This talk will present our efforts to use single-cell genomics to generate functional atlases of the genetic dependence of the response of cells to exposure. JOIN ZOOM MEETING Meeting ID: 999 0430 6839 password:seminar

"Empire of Pain: The Sackler Family and the Opioid Crisis," a conversation moderated by Carl Erik Fisher. For our first Narrative Medicine Rounds of 2022, on February 2nd, we are very excited to host Patrick Radden Keefe, author of EMPIRE OF PAIN: The Secret History of the Sackler Dynasty, in a conversation moderated by Carl Erik Fisher.  Empire of Pain is a grand, devastating portrait of three generations of the Sackler family, famed for their philanthropy, whose fortune was built by Valium and whose reputation was destroyed by OxyContin. An instant bestseller, winner of the Baillie Gifford Prize, and named one of the best books of 2021 by the New York Times, Time, The Economist, Boston Globe, Guardian, The Times (London), The Atlantic, Businessweek, Financial Times, NPR, Los Angeles Times, Newsweek, and many others, the book is a masterfully researched and reported work of nonfiction, and tells a history that absolutely all of us should know.  Keefe will be in conversation with Carl Erik Fisher, whose book THE URGE: Our History of Addiction, will be published on January 25, 2022. THE URGE is an authoritative, illuminating, and deeply humane history of addiction—a phenomenon that remains baffling and deeply misunderstood despite having touched countless lives—by an addiction psychiatrist striving to understand his own family and himself.