Human embryos often fail to cope with high levels of replication stress early in development. Their failure not only impairs fertility treatment but may have long-ranging impacts on our health.
Understanding what drives gut stem cells to work nonstop may reveal how idle stem cells elsewhere can be revved up to repair hearts, lungs, and brains. But are scientists studying the right cells?
A 24-hour fast followed by feeding rejuvenates the blood-forming stem cells in old mice, a finding that may lead to new ways to help people live healthier lives as they age.
A new study reveals how bone marrow stem cell niche generation is regulated, which could lead to improvements in stem cell transplantation for the treatment of blood diseases.
An over-the-counter cough suppressant can knock some heart cells back into rhythm, a finding that may lead to a new way to treat a rare heart condition.
An experimental gene therapy for sickle cell disease restored blood cells to their normal shape and eliminated severe pain crises for years after treatment, a multicenter study has found.
Cells used to study the human blood-brain barrier in the lab aren’t what they seem, a new study has found, throwing nearly a decade’s worth of research into question.
Hematopoietic stem cells can survive extraordinary stress. Columbia scientists have learned how they escape death, which could lead to new treatments for blood cancers and diseases related to aging.
Columbia scientists are using CRISPR to create stem cells that could ultimately alleviate diabetes in rare neonatal cases and may lead to a cell therapy for more common forms of the disease.
A new Science study from Columbia stem cell researchers has found that the liver is the surprising source of a growth factor that keeps bone marrow stem cells healthy.
3-D organoids created from the bladder cancers of patients mimic the characteristics of each patient’s tumor and may be used in the future to identify the best treatment for each patient.
Scientists at Columbia University Vagelos College of Physicians and Surgeons present the most definitive evidence to date that the human brain makes new neurons throughout life.