Columbia neuroscientists have identified a genetic mutation that fends off Alzheimer's in people at high risk and could lead to a new way to protect people from the disease.
With funding from the Ultra-rare Gene-based Therapy Network, scientists at Columbia and the n-Lorem Foundation will create tailor-made gene-based therapies for people with rare forms of ALS.
A study led by Columbia and Cornell researchers finds, surprisingly, that anticoagulants do not prevent recurrent strokes in people with one type of heart condition.
Increased connectivity in the brain's default mode network is a potential precursor, or biomarker, indicating a risk of developing major depressive disorder.
P&S researcher Wendy Chung and colleagues find genetic mutations that explain why many children with congenital heart disease also have neurodevelopmental disorders.
In a case demonstrating the promise of precision medicine, a 20-month-old girl suffering from a rare neurodegenerative disease was diagnosed by exome sequencing and successfully treated.
Funding from the ALS Association and the Tow Foundation will be used by the New York Genome Center to determine the entire genetic sequence of people with ALS who donated their tissues after death.