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An ancient antivirus system in our cells silences foreign DNA—but also hinders gene therapy. New research shows how the system could be disabled.
Columbia researchers have discovered that the human intestine has a reservoir of blood-forming stem cells and that the cells play a central role in the success of organ transplantation.
A new program at Columbia is looking for earlier signs of ALS so that future treatments can be delivered before extensive neurological damage occurs.
- October 4, 2017
Joachim Frank discusses the call from Sweden and his work using cryo-electron microscopy to reveal the three-dimensional shapes of biological molecules.
- October 2, 2017
Jeffrey Hall, Michael Rosbash, and Michael Young were awarded the 2017 Nobel Prize in Physiology or Medicine for their discoveries of molecular mechanisms controlling circadian rhythm.
- September 21, 2017
Macrophages can eat up to 70 dead cells a day, preventing atherosclerosis. A new CUMC study finds that mitochondria play a critical role in the process.
- September 8, 2017
Scientists have found compounds that can block transmission of the parasite that causes malaria and reduce resistance to currently available drugs.
- August 31, 2017
Columbia bioengineers and surgeons have developed a technique in animal models that overcomes a long-standing hurdle in lung regeneration.
- July 24, 2017
Columbia University Medical Center (CUMC) researchers have captured the first three-dimensional snapshots of the AMPA-subtype glutamate receptor in action.
- May 31, 2017
The discovery that pain receptors continue to function within nerves may lead to more effective pain medications with fewer side effects.
- May 30, 2017
Researchers report that CRISPR-Cas9 gene-editing technology can introduce hundreds of unintended mutations into the genome.
- May 11, 2017
Researchers have developed three-dimensional "mini organs," made from stem cells, that could be used to model lung diseases.