Columbia genome engineers are designing a CRISPR-based gene therapy with potential to prevent blindness in anyone with retinitis pigmentosa, a condition caused by more than 80 different genes.
Many Black Americans thought to have a high risk of developing kidney disease possess a genetic variant that eradicates the extra risk, a new study from Columbia researchers has found.
The genetic changes that made it possible for humans to walk upright have been uncovered in a study that also shows how slight variations in skeletal proportions are linked to arthritis.
Scientists from around the world attended a symposium at Columbia to celebrate the 80th birthday of Tom Maniatis and his contributions to the field of molecular biology.
Columbia's Sandra Soo-Jin Lee leads a national study on the inclusion of ethnic minorities in genetic studies with a goal of enhancing precision medicine.
A new study shows how certain cells ‘cheat’ during cell competition to eliminate their neighbors and take over tissues; the findings could point toward new strategies for treating cancer.
Lorraine S. Symington, PhD, the Harold S. Ginsberg Professor of Microbiology & Immunology, has been elected to the American Academy of Arts and Sciences.
Jeffrey Hall, Michael Rosbash, and Michael Young were awarded the 2017 Nobel Prize in Physiology or Medicine for their discoveries of molecular mechanisms controlling circadian rhythm.
Studies answer an old debate in developmental biology: How do cells destined to form a particular tissue or structure remember what they're supposed to be?
Solving a 60-year-old medical mystery, a team led by Columbia researchers has discovered what causes kidney and urinary tract defects in people with DiGeorge syndrome.