Ten years ago, a Columbia postdoc identified a simple nutrient that can alleviate Parkinson’s disease symptoms in mice by rewiring the brain. It’s finally being put to the test in people.
Established two decades ago, the essential tremor brain bank at Columbia has been instrumental in revealing the source and biology of a common but understudied neurodegenerative disorder.
Analysis of 1.6 million brain cells from older adults has captured the cellular changes that occur in Alzheimer’s early stages, revealing potential new targets and routes for prevention.
Columbia neurologists are investigating a set of blood tests that, used in combination with memory tests, may help physicians correctly diagnose Alzheimer disease in low-resource environments.
Columbia researchers have discovered how a genetic defect leads to spinal muscular atrophy, a finding that could lead to a new therapy for a disease that affects 1 in 6,000 children.
Columbia’s researchers have opened a trial of a noninvasive, focused ultrasound approach to open the blood-brain barrier, enabling higher concentrations of an effective drug to enter the brain.
Immune cells in the brain must rearrange a part of their cytoskeleton before they can perform their jobs, a finding that may lead to new ways to slow some brain diseases.
Indira Turney, an associate research scientist in the Department of Neurology, is studying how lived experiences affect they way the brain ages in diverse populations.