Columbia genome engineers are designing a CRISPR-based gene therapy with potential to prevent blindness in anyone with retinitis pigmentosa, a condition caused by more than 80 different genes.
That’s one of the first big challenges says Joachim Frank, a structural biologist at Columbia University in New York City who shared the 2017 Nobel Prize in Chemistry for his work on cryo-EM.
An analysis of more than 40,000 primary sensory neurons in the skin has found multiple different types, each sensing a more complex range of stimuli than previously assumed.
Editor's Note: Benjamin Lebwohl, the author of this First Opinion piece, is a professor of medicine in the Division of Digestive and Liver Diseases at the Vagelos College of Physicians and Surgeons.
