A region in the mouse brain records whether another individual is safe or threatening, a finding that may help researchers understand why some human conditions lead to social withdrawal.
Columbia biologists have developed inexpensive microscopy tools that capture high-level images of brain tissue, previously only possible with more expensive lab equipment.
With some of the world's leading neuroscientists and machine learning researchers, Columbia is seeking lessons from biology that can create AI systems as versatile and efficient as our brains.
Established two decades ago, the essential tremor brain bank at Columbia has been instrumental in revealing the source and biology of a common but understudied neurodegenerative disorder.
Deficiency of a protein in the hippocampus is a major cause of age-related memory loss, and this form of memory loss is reversible, according to Columbia researchers.
CUMC's Dr. Eric Kandel (2000 Nobel Laureate) said the project may lead to an understanding of "who we are as human beings and how we function and how these terrible diseases arise, and what we might be able to do address them more effectively."
The first evidence that selective activation of the dentate gyrus in the hippocampus can reduce anxiety without affecting learning - important therapeutic implications.