Ten years ago, a Columbia postdoc identified a simple nutrient that can alleviate Parkinson’s disease symptoms in mice by rewiring the brain. It’s finally being put to the test in people.
Established two decades ago, the essential tremor brain bank at Columbia has been instrumental in revealing the source and biology of a common but understudied neurodegenerative disorder.
Analysis of 1.6 million brain cells from older adults has captured the cellular changes that occur in Alzheimer’s early stages, revealing potential new targets and routes for prevention.
More symptoms of depression and lower cognitive status are independently associated with a more rapid decline in the ability to handle tasks of everyday living, according to a study by CUMC researchers.
The first evidence that selective activation of the dentate gyrus in the hippocampus can reduce anxiety without affecting learning - important therapeutic implications.