Uncertainty about the future has a way of taking over the mind, and a new study from Columbia neuroscientists is starting to reveal what changes take place in the unsure brain.
Columbia researchers have found a potential neurobiological mechanism for hallucinations and delusions that fits within the hierarchical model of psychosis and can explain their clinical presentation.
Columbia neuroscientists have identified neurons in mice that distinguish familiar companions from strangers and may help explain why people with schizophrenia struggle in social situations.
Columbia neuroscientists have described the activity of newly generated brain cells in awake mice—a process known as adult neurogenesis—and revealed the critical role these cells play in forming memories.
Zuckerman Institute researchers describe new approaches to systematically quantify the diverse types of neurons in the spinal cord that could be expanded to the rest of the nervous system.
In studies in mice, Zuckerman Institute researchers have discovered a way to restore memory deficits found in schizophrenia by regrowing lost neuronal connections.
Researchers describe a cellular circuit that helps the brain remember which environments are safe and which are harmful--and what can happen when that circuitry is disrupted.
A P&S research team has found that deficits seen in schizophrenia may be due to a decrease in the number of inhibitory neurons within the brain's memory center.