Study Gets to Heart of Norms for Elite Female Athletes

The first-ever cardiac study of elite female basketball players in the United States shows how their hearts adapt to intense physical training.

The study of 140 WNBA players also provides physicians with a frame of reference when screening for cardiac problems in female athletes.

The research is the result of a long-standing collaboration among cardiologists and researchers at Columbia University Irving Medical Center and NewYork-Presbyterian, the National Basketball Association and Women’s National Basketball Association, and the National Basketball and Women’s National Basketball Players Associations. The group has also created a screening and monitoring program for the leagues and guidelines for NBA and WNBA team physicians. The research team has previously reported similar data on male NBA players.

The new research, published online in JAMA Cardiology, also suggests that similar studies of female athletes are needed for other sports, which affect the heart in different ways.

Why study WNBA players?

Intense physical exercise increases the size, mass, and thickness of the walls of the heart.

“We call this ‘athlete's heart,’ and we’ve recognized this remodeling process for decades,” says David J. Engel, MD, associate professor of medicine at Columbia University Vagelos College of Physicians and Surgeons, a sports cardiologist at NewYork-Presbyterian/Columbia University Irving Medical Center, and senior author of the paper.

“But nearly all published data describes athletic changes in the hearts of male athletes. There is very little data on what an athletic heart looks like in elite female athletes and absolutely no data on the athletic heart in women who are professional basketball players.”

Team physicians and physicians who care for athletes need to know what a healthy heart in an elite athlete looks like, so that healthy hearts can be distinguished from those with signs of cardiac problems, including hypertrophic cardiomyopathy, an enlargement and thickening of the heart that can lead to life-threatening arrhythmias.

Among U.S. athletes, basketball players have been shown in epidemiologic studies to have the highest incidence of exercise-induced sudden cardiac death, though the incidence is lower for female athletes than for males.

In 2006, the NBA was the first professional sports league to implement a standardized preseason screening program that tests all of its players for heart disease. 

“But without normative data on how training for professional basketball affects heart structure compared with non-athletes or athletes from other sports, it isn’t easy to identify who is at risk,” says Sofia Shames, MD, assistant professor of medicine at Columbia University Vagelos College of Physicians and Surgeons, a cardiologist at NewYork-Presbyterian/Columbia University Irving Medical Center, and the study’s lead author.  

 

Basketball strengthens heart

In the study, the researchers analyzed cardiac ultrasound data of 140 WNBA athletes, all of whom had similar training, from the 2017 season.

The researchers found that the WNBA players generally have larger and thicker (more muscular) hearts than most women who are not athletes, and the differences can be attributed to a combination of the larger height of WNBA players and their physical conditioning. 

According to heart disease screening guidelines, which are based on data from the general population,  approximately 16% of the WNBA players could be inappropriately classified as having left ventricular enlargement.

Sofia Shames (CUIMC)

“The general population is not particularly athletic, and a physician who sees a heart the size of many WNBA players’ hearts would do further testing,” Shames says. “But in this group of women, these larger hearts are within the normal range for the athletes’ size and conditioning.”

“Evaluating the WNBA players on a large scale allows us to have comparison data for the future. Up until this research, some players were being sidelined until further tests could be done,” says Marci Goolsby, MD, team physician for the WNBA New York Liberty team, sports medicine physician at the Women’s Sports Medicine Center of the Hospital for Special Surgery, and a co-author of the paper. “We now have a much clearer picture of how to interpret data from preseason echocardiograms, and we can better determine who requires further testing.” 

The hearts of the WNBA players had also strengthened in different ways than the hearts of other female athletes. More than half of the WNBA players had heart walls greater than 1 cm in thickness, compared with less than 10% of Italian female athletes from a variety of sports.

The scans also showed that an important index of heart geometry—the thickness of the heart muscle in relation to diameter—was more prominent in the WNBA players compared to other female athletes.  

“That’s why we need reference data for players in each specific sport,” Engel adds. “If WNBA team physicians relied on the data from the European studies to screen players for heart disease, they would still be left with clinical questions. Our research can hopefully serve as a stimulus for more studies of female athletes in other sports.”

References

More information

The study is titled, “Echocardiographic Characterization of Female Professional Basketball Players in the U.S.” and was published online June 24 in JAMA Cardiology.

Additional authors are Natalie A. Bello (NYP/CUIMC), Allan Schwartz (NYP/CUIMC), Shunichi Homma (NYP/CUIMC), Nidhi Patel (NYP/CUIMC), Juan Garza (Heart and Vascular Institute of Texas, San Antonio, TX), Jonathan H. Kim (Emory University School of Medicine, Atlanta, GA), and John P. DiFiori (Hospital for Special Surgery, New York, NY, and NBA). 

The study was supported by funding from the WNBA as part of a medical services agreement between the WNBA and Columbia University Irving Medical Center.