Hachung Chung, PhD

Academic Appointments

  • Assistant Professor of Microbiology and Immunology
Hachung Chung, PhD

Departments and Divisions

  • Department of Microbiology & Immunology

NIH Grants

  • INVESTIGATING THE MECHANISM OF INTRINSIC TYPE I IFN PRODUCTION AND REGULATION IN THE BRAIN (Private)

    Jul 1 2020 - Jun 30 2023

Publications

Chung H. and Rice C.M. (2018) T time for ADAR: ADAR1 is required for T cell self-tolerance. EMBO Rep. 19: e47237.

Chung H., Calis J.J.A., Wu X., Sun T., Yu Y., Sarbanes S.L., Dao Thi V.L., Shilvock A.R., Hoffmann H.H., Rosenberg B.R. and Rice C.M. (2018) Human ADAR1 prevents endogenous RNA from triggering translational shutdown. Cell 172: 811-824 e14.

Yu Y., Scheel T.K.H., Luna J.M., Chung H., Nishiuchi E., Scull M.A., Echeverria N., Ricardo-Lax I., Kapoor A., Lipkin W.I., Divers T.J., Antczak D.F., Tennant B.C. and Rice C.M. (2017) miRNA independent hepacivirus variants suggest a strong evolutionary pressure to maintain miR-122 dependence. PLoS Pathology 13: e1006694.

Chung H., Pamp S.J., Hill J.A., Surana N.K., Edelman S.M., Troy E.B., Reading N.C., Villablanca E.J., Wang S., Mora J.R., Umesaki Y., Mathis D., Benoist C., Relman D.A. and Kasper D.L. (2012) Gut immune maturation depends on colonization with a host-specific microbiota. Cell 149:1578-1593.

Chung H. and Kasper D.L. (2010) Microbiota-stimulated immune mechanisms to maintain gut homeostasis. Curr. Opin. Immunol. 22: 455-460.

Duan J., Chung H., Troy E. and Kasper D.L. (2010) Microbial colonization drives expansion of IL-1 receptor 1-expressing and IL-17-producing gamma/delta T cells. Cell Host Microbe 7:140-150.

Gryllos I., Tran-Winkler H.J., Cheng M.F., Chung H., Bolcome R., 3rd, Lu W., Lehrer R.I. and Wessels M.R. (2008) Induction of group A Streptococcus virulence by a human antimicrobial peptide. Proc. Natl. Acad. Sci. U.S.A. 105: 16755-16760.

Ryndak M.B., Chung H., London E. and Bliska J.B. (2005) Role of predicted transmembrane domains for type III translocation, pore formation, and signaling by the Yersinia pseudotuberculosis YopB protein. Infect. Immun. 73: 2433-2443.