Luke Benvenuto, MD

Assistant Professor of Medicine at Columbia University Medical Center

Bio

Dr. Benvenuto completed his internship, residency and fellowship training at Columbia University Irving Medical Center/New York-Presbyterian and completed his final year of fellowship training specializing in lung transplantation in 2016.

Dr. Benvenuto’s academic and research interests include geographic donor lung allocation in the United States and disparities in waitlist/post-transplant outcomes. Dr. Benvenuto serves as the site principal investigator for Columbia’s multicenter collaborations through the Lung Transplant Outcomes Group (LTOG) and the Cystic Fibrosis Lung Transplant Consortium (CFLTC) that are aimed at improving outcomes before and after transplant. Finally, he also serves as a co-investigator for the clinical trials in lung transplantation at CUIMC, including Extracorporeal Photophersis for the Management of Progressive Bronchiolitis Obliterans Syndrome and the BREATH trials evaluating the efficacy of inhaled liposomal Cyclosporine for the treatment of Bronchiolitis Obliterans Syndrome.

Education and Training

Undergraduate:
University of Virginia, Charlottesville, VA 2002-2006, BA with High Distinction
Medical School:
The Mount Sinai School of Medicine, New York, NY, 2006-2010
Internship/Residency:
Columbia University Medical Center/New York Presbyterian, New York, NY, 2010-2013
Fellowship:
Pulmonary and Critical Care Medicine, Columbia University Medical Center/New York Presbyterian 2013-2016

Selected Honors and Awards

  • Alpha Omega Alpha Honor Medical Society: 2009
  • Gold Humanism Honor Society: 2009

Clinical

Specialties

  • Lung Transplant
  • Pulmonary Diseases
  • Critical care medicine

Clinical Expertise

  • Lung Transplantation
  • ILD
  • COPD/Emphysema

Board Certifications

  • Internal Medicine 2010
  • Pulmonary Medicine 2015
  • Critical Care Medicine 2016

Research

Research Interests

  • Geographic Disparities in Donor Lung Allocation
  • Improving equity of the lung allocation system and the lung allocation score (LAS)
  • Post lung transplant complications and survival

Selected Publications

  1. Benvenuto LJ, Snyder ME, Aversa M, Patel S, Shah L, Robbins HY, D’Ovidio F, Sonett J, Stanifer B, Lemaitre P, Arcasoy SM, Anderson M. Geographic differences in lung transplant Volume and Donor Availability during the COVID-19 pandemic. Transplantation. Apr 20201; 105(4): 861-866.
  2. Maheshwari, JA, Kolaitis NA, Anderson MR, Benvenuto L, gao Y, Katz PP, Greenland J, Wolters PJ, Covinsky K, Hays SR, Kukrja J Calabrese DR, Venado A, Shah RJ, Leard LE, Trinh B, Huang CY, Glidden D, Kleinhenz ME, Golden JA, Sutter N, Tietje-Ulrich G, Criner RN, Arcasoy SM, Christie JD, Diamond J, Singer JP. Construct and Predictive Validity of Sarcopenia in Lung Transplant Candidates. Ann Am Thorac Soc. 2021 Feb 10.
  3. Rudym D, Benvenuto LJ, Costa J, Avera M, Robbins H, Shah L, Kim H, Stanifer BP, Sonett J, D’Ovidio F, Arcasoy S. What awaits on the Other Side: Post-Lung Transplant Morbidity and Mortality After Pre-Transplant Hospitalization. Annals of Transplantation, 2020 Aug 18; 25:e922641.
  4. Aversa, M, Benvenuto LJ, Anderson M, Shah, L, Robbins H, Pereira M, Scheffert J, Carroll M, Hum J, Nolan M, Reilly G, Stanifer BP, D’Ovidio F, Sonett J, Arcasoy S. COVID-19 in lung transplant recipients: A single center case series from New York City. American Journal of Transplantation, 2020, August; 00:1-9.
  5. Benvenuto LJ, Costa J, Piloni D, Aversa M, Anderson MR, ShahL, Robbins HY, Stanifer B, Sonett HR, Arcasoy SM, D’Ovidio F. Right single lung transplant or double lung transplant compared with left single lung transplant in Chronic Obstructive Pulmonary Disease. Journal of Heart and Lung Transplantation, 2020, September; 39(9) 870-877.
  6. Anderson MR, Easthausen I, Gallagher G, Udupa J, Tong Y, Torigian D, Diamond J, Porteous M, Palmer S, Snyder L, Benvenuto L, Aversa M, Arcasoy S, Greenland JR, Hays S, Kukreja J, Cantu E, Kim J, Gallagher D, Baldwin M. Barr RG, Lederer DJ, Christie JD, Singer JP. Skeletal muscle adiposity and outcomes in candidates for lung transplantation: A Lung Transplant Body Composition Cohort Study. Thorax, 2020.
  7. Chen N, Spivack J, Cao T, Saqi A, Benvenuto LJ, Bulman W, Matthew M, Stoopler M, Arcasoy SA, Stanifer BP, Rizvi N, Shu CA. Characteristics and Outcomes of Lung Cancer in Solid Organ Transplant Recipients. Lung Cancer, 2020. Aug; 146:297-302.
  8. Pereira, M, Mohan S, Cohen D, Husain S, Dube G, Ratner L, Arcasoy S, Aversa M, Benvenuto LJ, Dadhania D, Kapur S, Dove L, Brown R, Rosenblatt R, Samstein B, Uriel N, Farr M, Satlin M, Small M, Walsh TJ, Kodiyanplakkal R, Miko B, Aaron J, Tsapepas D, Edmond J, Verna E. COVID-19 in solid organ transplant recipients: Initial report from the US epicenter. Am J Transplant. 2020 May; 00:1-9.
  9. Benvenuto LJ, Aversa M. Should We Accept This Offer? When Assessing Donor Lungs, Don’t Rely on Others. Annals of the American Thoracic Society. 2019 March; 16(3) 304-305.
  10. Aversa MA, Benvenuto LJ, Kim HP, Shah L, Robbins H, Stanifer BP, D’Ovidio F, Vasilescu E, Sonett JR, Arcasoy SA. Effect of Calculated Panel Reactive Antibody Value on Waitlist Outcomes for Lung Transplant Candidates. Ann Transplant, 2019; 24:383-392
  11. Snyder ME, Finalyson MO, Connors TJ, Dogra P, Senda T, Bush E, Carpenter D, Marboe C, Benvenuto L, Shah L, Robbins H, Hook JL, Sykes M, D’Ovidio F, Bacchetta M Sonett JR, Lederer DJ, Arcasoy S, Sims PA, Farber DL. Generation and persistence of human tissue-resident memory T cells in lung transplantation. Science Immunology, 2019 Mar; 4(33).
  12. Benvenuto LJ, Anderson DA, Kim HP, Hook JL, Shah L, Robbins H, D’Ovidio F, Bacchetta M, Sonett JR, and Arcasoy SA. Geographic disparities in donor lung supply and lung transplant waitlist outcomes: A cohort study. Am J Transplant. 2018 Jun; 18(6) 1471-1480.
  13. Benvenuto LJ, Anderson MR, Arcasoy SM. New frontiers in immunosuppression. Journal of Thoracic Disease, 2018; May;10(5):3141-3155
  14. Costa, J, Benvenuto LJ, Sonett JR. Long Term Outcomes and Management of the Lung Transplant Recipient. Best Practice and Research Clinical Anaesthesiology. 2017 Jun; 31(2) 285-297.
  15. Benvenuto LJ, Krakoff LR. Morbidity and mortality of orthostatic hypotension: Implications for management of Cardiovascular disease. Am J Hypertens. 2011 Feb; 24 (2): 135-44.
  16. Zafonte BT, Liu S, Lynch-Kattman M, Torregroza I, Benvenuto L, Kennedy M, Keller G, Evans T. Smad1 expands the hemangioblast population within a limited developmental window. Blood. 2007 Jan; 15109(2): 516-23.