Aimee M. Layton, PhD

Associate Research Scientist in the Department of Medicine


Dr. Layton is an Associate Research Scientist in the Dept. of Medicine and the Cardiopulmonary Exercise Laboratory Director. Dr. Layton has been a principal investigator of eight studies investigating exercise outcome measures in a variety of patient populations. She also leads one of the only respiratory mechanics laboratories with publications demonstrating alterations of respiratory mechanics in both diseased and healthy populations. Dr. Layton is a respected expert in clinical exercise physiology and has lectured internationally on the topic. Beyond her research, Dr. Layton has been performing exercise testing and counseling for patients with pulmonary disease for a decade. Dr. Layton plays an important role as the exercise physiologist for the pulmonary division at Columbia University Medical Center, testing, exercise counseling and performing research involving patients with all stages of pulmonary disease.

Education and Training

B.S. in Exercise Science, University of Massachusetts Amherst, Amherst, MA May 2005
Graduate School:
M.A. in Applied Physiology, Columbia University, Teacher’s College, New York, NY 2007
Doctoral Degree:
Ph.D. in Kinesiology, Dissertation in Ventilatory Mechanics, Graduate School of Arts and Sciences, Columbia University, 2013

Professional Membership

  • Member of the American College of Sports Medicine (ACSM)
  • Member of the International Society of Heart & Lung Transplantion (ISHLT)
  • Member of the American Thoracic Society (ATS)
  • Member of the American Physiology Society (APS)


Research Interests

  • Ventilatory Biomechanics
  • Pulmonary Rehabilitation and impact of pulmonary disease on response to exercise

Selected Publications

  1. Layton AM, Armstrong HF, Baldwin MR, Podolanczuk AJ, Pieszchata NM, Singer JP, D’Ovidio F, Meza KS, Arcasoy SM, Lederer DJ. Frailty and maximal exercise capacity in adult lung transplant candidates. Resp. Med. 2017 October; 131: 70-76
  2. Layton AM, Armstrong HF, Kim HP, D’Ovidio F, Meza KS, Arcasoy SM. Cardiopulmonary Exercise Factors Predictive of One-year Transplant-free Survival in Interstitial Lung Disease. Respir Med. 2017 May; 126: 59-67.
  3. Layton AM, Moran SL, Choudhury AR, Hupf J, Thomashow BM and Mitsumoto H. Non-invasive, non-effort dependant measurement of abnormal ventilatory mechanics in Amyotrophic Lateral Sclerosis (ALS). Muscle and Nerve. 2016; 54: 270-276.
  4. Layton AM. Update in Exercise Testing. Current Physical Medicine and Rehabilitation Reports. 21 July 2015. DOI:10.1007/s40141-015-0095-0.
  5. Layton AM, Armstrong HF, Moran SL, Guenette JA, Thomashow BM, Jellen PA, Bartels MN, Sheel AW, Basner RC. Quantification of Improvements in Static and Dynamic Ventilatory Measures Following Lung Volume Reduction Surgery for Severe COPD. JCOPDF. 2015; 2 (1).
  6. Layton AM, Whitworth JW, Peacock J, Bartels MN, Jellen PA, Thomashow BM. Feasibility and Acceptability of Utilizing a Smartphone Based Application to Monitor Outpatient Discharge Instruction Compliance in Cardiac Disease Patients Peri-discharge from Hospitalization. Int J Telemed Appl. 2014 Nov 11.1.
  7. Layton AM, Moran SL, Garber CE, Armstrong HF, Basner RC, Thomashow BM, Bartels MN. Optoelectronic plethysmography compared to spirometry during maximal exercise. Respir Physiol Neurobiol. 2013 Jan 15;185(2):362-8.
  8. Layton AM, Garber CE, Basner RC, Bartels MN. An assessment of pulmonary function testing and ventilatory kinematics by optoelectronic plethysmography. Clin Physiol Funct Imaging. 2011 Sept; 31(5):333-6.
  9. Layton AM, Garber CE, Thomashow BM, Gerardo RE, Emmert-Aronson BO, Armstrong HF, Basner RC, Jellen P, Bartels MN. Exercise ventilatory kinematics in endurance trained and untrained men and women. Resp Physiol Neurbiol. 2011 Sep 15; 178 (2):223-9.

View Dr. Layton's full list of publications from PubMed