2018 Louisa Gross Horwitz Prize Lectures
Ronald M. Evans, PhD
Investigator, Howard Hughes Medical Institute
Professor, Salk Institute for Biological Studies
“Controlling Genes to Corral Cancer”
Monday, October 29, 2018
Davis Auditorium (Rm. 412), Schapiro Center (CEPSR)
530 W. 120th St.
Ronald M. Evans, Ph.D., is a professor at the Salk Institute for Biological Studies, a Howard Hughes Medical Institute Investigator, and holder of the March of Dimes Chair in Developmental and Molecular Biology at the Salk Institute. He is also a Lustgarten Distinguished Scholar, Director of the Salk’s Gene Expression Laboratory and Metabolic Engineering Program, and Co-Director of the Helmsley Center for Genomic Medicine. He is known for pioneering studies on hormones’ normal activities and their roles in disease, including a major discovery of nuclear hormone receptors, which respond to steroid hormones, vitamin A, vitamin D, thyroid hormones, and bile acids. By targeting genes these receptors help control sugar, salt, calcium, cholesterol, and fat metabolism. They are primary targets in breast, prostate, and pancreatic cancers and leukemia treatment and have therapeutic roles in chronic inflammation, osteoporosis, and type 2 diabetes and asthma. His muscle metabolism studies led to the discovery of exercise mimetics, which promote the benefits of fitness without training and may help battle the obesity epidemic, diabetes, heart disease, and frailty. Evans is a co-leader of four Stand Up to Cancer Dream Teams. He was awarded the Albert Lasker Basic Medical Research Award in 2004 and the Wolf Prize in Medicine in 2012. He is a member of the NAS, NAM, and NAI.